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Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufman-Wolf, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis) в виде монокультур и микробных ассоциаций, включая грибковую микрофлору с резистентностью к химиотерапевтическим препаратам.\n\nОбладает противовирусным действием, активен в отношении сложноустроенных вирусов (вирусы герпеса, вирус иммунодефицита человека).\n\nМирамистин® действует на возбудителей заболеваний, передающихся половым путем (Chlamydia spp.,Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae).\n\nЭффективно предотвращает инфицирование ран и ожогов. Активизирует процессы регенерации. Стимулирует защитные реакции в месте применения, за счет активации поглотительной и переваривающей функции фагоцитов потенцирует активность моноцитарно-макрофагальной системы. Обладает выраженной гиперосмолярной активностью, вследствие чего купирует раневое и перифокальное воспаление, абсорбирует гнойный экссудат. Не повреждает грануляции и жизнеспособные клетки кожи, не угнетает краевую эпителизацию.\n\nНе обладает местнораздражающим действием и аллергизирующими свойствами.\n\n##### ФАРМАКОКИНЕТИКА\n\nПри местном и наружном применении Мирамистин® не обладает способностью всасываться через кожу и слизистые оболочки.\n\n##### ПОКАЗАНИЯ К ПРИМЕНЕНИЮ\n\n * профилактика и лечение воспалительных заболеваний в гинекологии (вульвовагинита, бактериального вагиноза);\n * профилактика и лечение нагноений послеродовых травм, ран влагалища, послеродовых инфекций.\n\n\n\n##### МКБ-10\n\nКод МКБ-10| Показание \n---|--- \nN76| Другие воспалительные болезни влагалища и вульвы \nO86.0| Инфекция хирургической акушерской раны \nO86.1| Другие инфекции половых путей после родов \n \n##### ПРОТИВОПОКАЗАНИЯ\n\n * повышенная чувствительность к действующему веществу или компонентам препарата;\n * детский возраст до 18 лет.\n\n\n\n##### ПРИМЕНЕНИЕ ПРИ БЕРЕМЕННОСТИ И КОРМЛЕНИИ ГРУДЬЮ\n\nСогласно имеющимся данным применение препарата при беременности и в период грудного вскармливания возможно, т.к. препарат не обладает системным действием при его использовании в соответствии с инструкцией.\n\nПеред применением препарата при беременности, при предполагаемой беременности или при планировании беременности необходимо проконсультироваться с врачом.\n\nПеред применением препарата, если пациентка беременна, или предполагает, что могла бы быть беременной, или планирует беременность, необходимо проконсультироваться с врачом.\n\nПеред применением препарата в период грудного вскармливания необходимо проконсультироваться с врачом.\n\n##### ПРИМЕНЕНИЕ ДЕТЬМИ\n\nПротивопоказано применение препарата у детей и подростков до 18 лет.\n\n##### СПОСОБ ПРИМЕНЕНИЯ И ДОЗЫ\n\nИнтравагинально.\n\nПеред применением суппозиторий освобождают от контурной упаковки.\n\nНазначают по 1 суппозиторию 10 мг 2 раза/сут (с интервалом 12 ч) или по 1 суппозиторию 15 мг 1 раз/сут (с интервалом 24 ч) в течение 7 дней.\n\nВводить суппозиторий как можно глубже во влагалище; не использовать мыло или другие средства на основе мыла для туалета половых органов на протяжении 2 ч до и 2 ч после интравагинального введения Мирамистина® (для этого следует использовать только чистую воду).\n\nЕсли после лечения улучшения не наступает, или симптомы усугубляются, или появляются новые симптомы, необходимо проконсультироваться с врачом. Рекомендуется применять препарат только согласно тому способу применения и в тех дозах, которые указаны в инструкции.\n\n##### ПОБОЧНОЕ ДЕЙСТВИЕ\n\nБезопасность применения Мирамистина® в виде суппозиториев оценивали у небеременных женщин в клинических исследованиях.\n\nВсе зарегистрированные нежелательные реакции (НР) были легкой степени тяжести и характеризовались локализацией в месте введения.\n\nПараметры частоты НР определяются следующим образом: очень часто (≥1/10); часто (≥1/100, но <1/10); нечасто (≥1/1000, но <1/100); редко (≥1/10000, но <1/1000); очень редко (<1/10000); частота неизвестна (не может быть оценена по имеющимся данным.\n\nСистемно-органный \nкласс| Нежелательная реакция| Частота \n---|---|--- \nОбщие нарушения и реакции в месте введения| Зуд в месте введения| Часто (≥1/100, но <1/10) \nДискомфорт в месте введения| Часто (≥1/100, но <1/10) \nЖжение в месте введения| Часто (≥1/100, но <1/10) \nБоль в области нижней трети живота| Нечасто (≥1/1000, но <1/100) \nСухость влагалища| Нечасто (≥1/1000, но <1/100) \nУсиление сосудистого рисунка по передней губе шейки матки| Нечасто (≥1/1000, но <1/100) \nНарушения со стороны репродуктивной системы и молочных желез| Незначительные нетипичные выделения из влагалища| Часто (≥1/100, но <1/10) \nДисбиоз влагалища| Нечасто (≥1/1000, но <1/100) \nВагинит| Нечасто (≥1/1000, но <1/100) \nЛабораторные и инструментальные данные| Дрожжеподобные грибы во влагалищном мазке| Нечасто (≥1/1000, но <1/100) \nЛейкоцитоз во влагалищном мазке| Нечасто (≥1/1000, но <1/100) \n \nЕсли отмечаются побочные эффекты, указанные в инструкции по медицинскому применению, или они усугубляются, или отмечаются любые другие эффекты, не указанные в инструкции, пациенту необходимо сообщить об этом врачу.\n\n##### ПЕРЕДОЗИРОВКА\n\nСлучаев передозировки препарата при местном или наружном применении не зарегистрировано.\n\n##### ВЗАИМОДЕЙСТВИЕ С ДРУГИМИ ЛЕКАРСТВЕННЫМИ ПРЕПАРАТАМИ И ДРУГИЕ ВИДЫ ВЗАИМОДЕЙСТВИЯ\n\nПри одновременном применении с антибиотиками отмечено усиление их противобактериальных и противогрибковых свойств.\n\nСредства, содержащие анионные ПАВ (мыльные растворы), могут инактивировать препарат.\n\n##### ОСОБЫЕ УКАЗАНИЯ\n\nПрепарат предназначен для интравагинального применения у взрослых пациентов.\n\nДля предотвращения реинфицирования рекомендуется одновременное лечение половых партнеров.\n\nВ период лечения бактериального вагиноза рекомендуется воздерживаться от половых контактов.\n\nТуалет наружных половых органов не влияет на эффективность и переносимость суппозиториев вагинальных Мирамистин®, т.к. препарат применяется интравагинально, однако следует иметь в виду, что антимикробное действие препарата может быть снижено анионными поверхностно-активными веществами, такими как мыло.\n\nВлияние на способность к управлению транспортными средствами и механизмами\n\nПрименение препарата не оказывает влияния на способность управлять транспортными средствами, механизмами.\n\n##### СРОК ГОДНОСТИ\n\nСрок годности - 2 года. 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МИРАМИСТИН СУПП ВАГИН 15МГ №10

ФАРМАКО-ТЕРАПЕВТИЧЕСКАЯ ГРУППА