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ФАРМАКО-ТЕРАПЕВТИЧЕСКАЯ ГРУППА\n\nжелез желудка секрецию понижающее средство - протонного насоса ингибитор\n\n##### КОД АТХ\n\nA02BC05 - Эзомепразол\n\n##### ПОКАЗАНИЯ К ПРИМЕНЕНИЮ\n\n** _Гастроэзофагеальная рефлюксная болезнь (ГЭРБ)_**\n\n_Лечение эрозивного рефлюкс-эзофагита:_\n\n * длительное поддерживающее лечение после заживления эрозивного рефлюкс-эзофагита, профилактика рецидивов;\n * симптоматическое лечение ГЭРБ.\n\n\n\n**_Язвенная болезнь желудка и двенадцатиперстной кишки в составе комбинированной терапии:_**\n\n * лечение язвы двенадцатиперстной кишки, ассоциированной с Helicobacter pylori;\n * профилактика рецидивов пептической язвы, ассоциированной с Helicobacter pylori.\n\n\n\n**_Длительная кислотоподавляющая терапия у пациентов, перенесших кровотечение из пептической язвы (после в/в применения препаратов, понижающих секрецию желез желудка, для профилактики рецидива)_**\n\n_Пациенты, длительно принимающие НПВП:_\n\n * лечение язвы желудка, обусловленной приемом НПВП;\n * профилактика язвы желудка и двенадцатиперстной кишки, обусловленной приемом НПВП у пациентов, относящихся к группе риска.\n\n\n\n_**Синдром Золлингера-Эллисона или другие состояния, характеризующиеся патологической гиперсекрецией желез желудка, в т.ч. идиonатическая гиперсекреция**_\n\n##### МКБ-10\n\nКод МКБ-10| Показание \n---|--- \nB98.0| Helicobacter pylori как причина болезней, классифицированных в других рубриках \nE16.4| Нарушение секреции гастрина (гипергастринэмия, синдром Золлингера-Эллисона) \nE16.8| Другие уточненные нарушения внутренней секреции поджелудочной железы \nK21| Гастроэзофагеальный рефлюкс \nK21.0| Гастроэзофагеальный рефлюкс с эзофагитом \nK25| Язва желудка \nK26| Язва двенадцатиперстной кишки \nK27| Пептическая язва \nY45| Аналгезирующие, жаропонижающие и противовоспалительные средства \n \n##### ПРОТИВОПОКАЗАНИЯ\n\n * повышенная чувствительность к эзомепразолу, замещенным бензимидазолам или другим компонентам препарата;\n * детский возраст до 12 лет (в связи с отсутствием данных об эффективности и безопасности применения препарата у данной группы пациентов);\n * детский возраст от 12 до 18 лет по всем показаниям, кроме ГЭРБ;\n * одновременный прием с атазанавиром и нелфинавиром.\n\n\n\n_С осторожностью_\n\nТяжелая почечная недостаточность (опыт применения ограничен).\n\n##### СПОСОБ ПРИМЕНЕНИЯ И ДОЗЫ\n\nВнутрь. Таблетку следует проглатывать целиком, не разжевывая, запивая достаточным количеством воды.\n\n**Взрослые и дети с 12 лет**\n\n** _Гастроэзофагеальная рефлюксная болезнь_**\n\n _Лечение эрозивного рефлюкс-эзофагита:_ по 40 мг 1 раз/сут в течение 4-х недель.\n\nРекомендуется дополнительный 4-х недельный курс лечения в случаях, когда после первого курса заживление эзофагита не наступает или, сохраняются симптомы.\n\n_Длительное поддерживающее лечение после заживления эрозивного рефлюкс-эзофагита, профилактика рецидивов:_ по 20 мг 1 раз/сут. \n\n_Симптоматическое лечение ГЭРБ:_ 20 мг 1 раз/сут пациентам без эзофагита. Если после 4-х недель лечения симптомы не исчезают, следует провести дополнительное обследование пациента. После устранения симптомов можно перейти на режим приема препарата \"при необходимости\" - 20 мг 1 раз/сут при возобновлении симптомов. Для пациентов, принимающих НПВП и относящихся к группе риска развития язвы желудка или двенадцатиперстной кишки, не рекомендуется лечение в режиме \"при необходимости\".\n\n**Взрослые**\n\n** _Язвенная болезнь желудка и двенадцитиперстной кншкн_**\n\n _В составе комбинированной терапии для эраднкации Helicobacter pylori:_\n\n * лечение язвы двенадцатиперстной кишки, ассоциированной с Helicobacter pylori: Эзомепразол Канон 20 мг, амоксициллин 1000 мг и кларитромицин 500 мг. Все препараты принимаются 2 раза/сут в течение 1 недели;\n * профилактика рецидивов пептической язвы, ассоциированной с Helicobacter pylori: Эзомепразол Канон 20 мг, амоксициллин 1000 мг и кларитромицин 500 мг. Все препараты принимаются 2 раза/сут в течение 1 недели.\n\n\n\n_Длительная кнслотоподавляющая терапия у пациентов, перенесших кровотечение из пептической язвы (после в/в применения препаратов, понижающих секрецию желез желудка, для профилактики рецидива):_ Эзомепразол Канон 40 мг 1 раз/сут в течение 4 недель после в/в применения препаратов, понижающих секрецию желез желудка.\n\n**_Пациенты, длительно принимающие НПВП_**\n\n _Лечение язвы желудка, обусловленной приемом НПВП:_ Эзомепразол Канон 20 мг 1 раз/сут; длительность лечения 4-8 недель.\n\n_Профилактика язвы желудка и двенадцатиперстной кишки, обусловленной приемом НПВП:_ Эзомепразол Канон 20 мг 1 раз/сут.\n\n_**Состояния, характеризующиеся патологической гиперсекрецией желез желудка, в т.ч. синдром Золлингера-Эллисона и идиопатическая гиперсекреция:**_ рекомендуемая начальная доза препарата Эзомепразол Канон 40 мг 2 раза/сут. Далее доза подбирается индивидуально, длительность лечения определяется клинической картиной заболевания. Имеется опыт применения от 80 до 160 мг эзомепразола в сутки, при приеме препарата более 80 мг/сут рекомендуется разделить необходимую дозу на 2 приема.\n\n**_Почечная недостаточность:_** коррекции дозы препарата Эзомепразол Канон не требуется. Однако опыт применения эзомепразола у пациентов с тяжелой почечной недостаточностью ограничен, в связи с этим, при назначении препарата этой категории пациентов следует соблюдать осторожность.\n\n_**Печеночная недостаточность:**_ при печеночной недостаточности легкой и средней степени тяжести коррекции дозы не требуется. Для пациентов с тяжелой печеночной недостаточностью максимальная суточная доза не должна превышать 20 мг.\n\n**_Пациенты пожилого возраста:_** коррекция дозы препарата не требуется.\n\n##### ПОБОЧНОЕ ДЕЙСТВИЕ\n\nКлассификация частоты развития побочных эффектов ВОЗ: очень часто - ≥1/10 назначений (>10%); часто - от ≥1/100 до <1/10 назначений (>1% и <10%); нечасто - от ≥1/1000 до <1/100 назначений (>0.1% и <1%); редко - от ≥1/10000 до <1/1000 назначений (>0.01% и <0.1%); очень редко - <1/10000 назначений (<0.01%); частота неизвестна - не может быть оценена на основе имеющихся данных. В каждой группе нежелательные эффекты представлены в порядке уменьшения их серьезности.\n\n_Нарушения со стороны нервной системы_ : часто - головная боль; нечасто - сонливость, бессонница, головокружение, парестезии; редко - возбуждение, замешательство, депрессия; очень редко - агрессивное поведение, галлюцинации.\n\n_Нарушения со стороны дыхательной системы:_ редко - бронхоспазм.\n\n_Нарушения со стороны пищеварительной системы:_ часто - боль в животе, диарея, метеоризм, тошнота, рвота, запор; нечасто - сухость во рту, повышение активности \"печеночных\" ферментов; редко - стоматит, кандидоз ЖКТ, гепатит (с- желтухой или без); очень редко - печеночная недостаточность, печеночная энцефалопатия у пациентов с заболеваниями печени в анамнезе, микроскопический колит. \n\n_Нарушения со стороны почек и мочевыводящих путей:_ очень редко - интерстициальный нефрит; частота неизвестна - почечная недостаточность.\n\n_Нарушения со стороны репродуктивной системы:_ очень редко - гинекомастия.\n\n_Нарушения со стороны опорно-двигательного аппарата:_ редко - артралгия, миалгия; очень редко - мышечная слабость; частота неизвестна - переломы шейки бедра, костей запястья, позвонков. \n\n_Нарушения со стороны кожных покровов:_ нечасто - зуд, сыпь, крапивница, дерматит, периферические отеки; редко - алопеция, фотосенсибилизация, недомогание, повышенная потливость; очень редко - синдром Стивенса-Джонсона, токсический эпидермальный некролиз, мультиформная эритема.\n\n_Нарушения со стороны органов кроветворения:_ редко - лейкопения, тромбоцитопения; очень редко - агранулоцитоз, панцитопения.\n\n_Нарушения со стороны органа чувств:_ нечасто - нечеткость зрения; редко - нарушение вкуса.\n\n_Аллергические реакции:_ редко - реакции гиперчувствительности (например, лихорадка, ангионевротический отек, анафилактическая реакция/анафилактический шок).\n\n_Лабораторные и инструментальные данные:_ редко - гипонатриемия; очень редко - гипомагниемия, гипокальциемия вследствие тяжелой гипомагниемии, гипокалиемия вследствие тяжелой гипомагниемии.\n\n##### СРОК ГОДНОСТИ\n\nСрок годности - 2 года.\n\nНе применять по истечении срока годности.\n\n##### УСЛОВИЯ ХРАНЕНИЯ\n\nПрепарат следует хранить в сухом, защищенном от света и недоступном для детей месте 25°С. \n\n##### УСЛОВИЯ ОТПУСКА\n\nПо рецепту\n\n##### ПРОТИВОПОКАЗАНИЯ\n\n * повышенная чувствительность к эзомепразолу, замещенным бензимидазолам или другим компонентам препарата;\n * детский возраст до 12 лет (в связи с отсутствием данных об эффективности и безопасности применения препарата у данной группы пациентов);\n * детский возраст от 12 до 18 лет по всем показаниям, кроме ГЭРБ;\n * одновременный прием с атазанавиром и нелфинавиром.\n\n\n\n_С осторожностью_\n\nТяжелая почечная недостаточность (опыт применения ограничен).","overSized","imageComparisonOptions",[],"reviewsCounters",{},"redemptionStats",[],"saleEndsDateIso","cashback","showMultipleFractionsCounter","promoTitle","promoDescription","promoLegalDescription","lowestRecentPrice","productDisclaimers",[1102],{"_1103":1104,"_274":1105},"details","Цена действительна только при заказе онлайн. 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ЭЗОМЕПРАЗОЛ КАНОН ТАБ П/О К/Р 40МГ №14

ФАРМАКО-ТЕРАПЕВТИЧЕСКАЯ ГРУППА