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При нанесении на слизистые оболочки носа вследствие сосудосуживающего действия препарат уменьшает отечность. В результате, проходимость носовых ходов быстро восстанавливается, носовое дыхание надолго облегчается.\n\nДействие препарата начинается в течение первых 5 мин и продолжается 8-10 ч.\n\n##### ФАРМАКОКИНЕТИКА\n\nФармакокинетические исследования у человека не проводились. Фармакокинетика трамазолина изучена на крысах, кроликах и обезьянах. Показано, что после применения препарата внутрь или интраназально всасывается 50-80% введенной дозы. Трамазолин и его метаболиты распределяются во всех внутренних органах, наивысшая концентрация с постоянством обнаруживается в печени.\n\nПосле перорального или местного применения основные метаболиты определяются в моче. 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На более поздних сроках беременности применение препарата Лазолван® Рино допускается только после консультации с врачом.\n\nБезопасность применения препарата Лазолван® Рино в период грудного вскармливания не подтверждена. Применение препарата в период грудного вскармливания допускается только после консультации с врачом.\n\nИсследования о влиянии препарата Лазолван® Рино на фертильность не проводились. На основе имеющихся данных отсутствуют упоминания о возможном влиянии трамазолина гидрохлорида на фертильность.\n\n##### ПРИМЕНЕНИЕ ДЕТЬМИ\n\nПротивопоказан в детском возрасте до 6 лет.\n\n##### СПОСОБ ПРИМЕНЕНИЯ И ДОЗЫ\n\n**Взрослым и детям с 6 лет** \\- по 1 впрыскиванию в каждый носовой ход (до 4 впрыскиваний в каждый носовой ход в день).\n\nНе следует применять препарат более 5-7 дней без назначения врача.\n\n**Инструкция по использованию флакона с дозирующим устройством**\n\nПеред впрыскиванием следует очистить носовые ходы.\n\n 1. Снять защитный колпачок.\n 2. Перед первым использованием необходимо произвести несколько впрыскиваний в воздух до появления устойчивого облака аэрозоля. После этого дозирующее устройство готово к использованию. \n 3. Держа голову прямо, ввести наконечник в носовой ход и произвести одно впрыскивание.\n\n\n\nПовторить процедуру для другого носового хода. После извлечения наконечника произвести обычный вдох через нос.\n\n 1. Надеть защитный колпачок.\n\n\n\nРекомендуется очищать наконечник после каждого использования.\n\n##### ПОБОЧНОЕ ДЕЙСТВИЕ\n\n _Со стороны нервной системы:_ редко (≥0.01% и <0.1%) - головокружение, нарушения вкусовых ощущений; нечасто (≥0.1% и <1%) - головная боль; частота не установлена* - сонливость, седативный эффект.\n\n_Со стороны психики:_ нечасто (≥0.1% и <1%) - беспокойство; частота не установлена* - галлюцинации, бессонница.\n\n_Со стороны сердечно-сосудистой системы:_ нечасто (≥0.1% и <1%) - сердцебиение; частота не установлена* - аритмия, тахикардия, увеличение АД.\n\n_Со стороны органов дыхания, органов грудной клетки и средостения:_ часто (≥1% и <10%) - назальный дискомфорт; нечасто (≥0.1% и <1%) - отек носа, сухость в носу, ринорея, чиханье; редко (≥0.01% и <0.1%) - носовое кровотечение.\n\n_Со стороны пищеварительной системы:_ нечасто (≥0.1% и <1%) - тошнота.\n\n_Со стороны иммунной системы:_ частота не установлена* - гиперчувствительность.\n\n_Со стороны кожи и подкожных тканей**:_ частота не установлена* - сыпь, зуд, отек кожи.\n\n_Прочие:_ частота не установлена* - отек слизистой оболочки**, утомляемость.\n\n* Нежелательные явления, связь которых с препаратом расценивалась как возможная, зарегистрированные при широком применении препарата. Частоту этих редких явлений трудно оценить.\n\n** Как симптомы повышенной чувствительности.\n\n##### ПЕРЕДОЗИРОВКА\n\n _Симптомы:_ вслед за повышением АД и тахикардией возможно (особенно у детей) падение АД, развитие шока, рефлекторной брадикардии, понижение температуры тела. \n\nПо аналогии с другими альфа-симпатомиметиками клиническая картина интоксикации может быть неотчетливой, поскольку фазы стимуляции и депрессии ЦНС и сердечно-сосудистой системы могут сменять друг друга.\n\nОсобенно у детей интоксикация приводит к воздействиям на ЦНС с развитием судорог и комы, брадикардии, угнетения дыхания. Симптомами стимуляции ЦНС являются тревожность, возбуждение, галлюцинации и судороги. К симптомам угнетения ЦНС относят снижение температуры тела, вялость, сонливость и кому.\n\nКроме того, возможно развитие следующих симптомов: мидриаз, миоз, повышенное потоотделение, лихорадка, бледность, цианоз губ, нарушения функций сердечно-сосудистой системы (включая остановку сердца); нарушение дыхания (включая дыхательную недостаточность, остановку дыхания); психологические нарушения. \n\n_Лечение:_ в случае назальной передозировки немедленно промойте или очистите нос. Может потребоваться симптоматическое лечение.\n\n##### ВЗАИМОДЕЙСТВИЕ С ДРУГИМИ ЛЕКАРСТВЕННЫМИ ПРЕПАРАТАМИ И ДРУГИЕ ВИДЫ ВЗАИМОДЕЙСТВИЯ\n\nНекоторые антидепрессанты (ингибиторы МАО и трициклические антидепрессанты) и сосудосуживающие препараты при одновременном назначении могут вызвать повышение АД.\n\nКомбинированный прием с трициклическими антидепрессантами может привести к развитию аритмии.\n\nОдновременный прием с антигипертензивными средствами (особенно с теми, которые влияют на симпатическую нервную систему) может привести к различным кардиоваскулярным эффектам.\n\n##### ОСОБЫЕ УКАЗАНИЯ\n\nЕсли после 7 дней приема препарата положительной динамики симптомов не отмечается, следует решать вопрос о прекращении приема препарата или о продолжении лечения. Длительное применение назальных сосудосуживающих препаратов может привести к развитию хронического воспаления и заложенности носа, а также к атрофии слизистой оболочки носа. \n\nСледует избегать попадания препарата в глаза.\n\n_Влияние на способность к управлению транспортными средствами и механизмами_\n\nИсследования по влиянию препарата на способность управлять автомобилем и машинным оборудованием не проводились. Однако при приеме препарата возможны такие нежелательные эффекты как галлюцинация, сонливость, седативный эффект, головокружение и усталость. Поэтому необходимо соблюдать осторожность при управлении автомобилем и машинным оборудованием.\n\nПри появлении вышеперечисленных побочных эффектов необходимо избегать выполнения таких потенциально опасных задач, как управление автомобилем и машинным оборудованием.\n\n##### СРОК ГОДНОСТИ\n\nСрок годности - 3 года. Не использовать по истечении срока годности. \n\n##### УСЛОВИЯ ХРАНЕНИЯ\n\nПрепарат следует хранить в недоступном для детей месте при температуре не выше 25°С. \n\n##### УСЛОВИЯ ОТПУСКА\n\nОтпускают без рецепта\n\n##### ПРОТИВОПОКАЗАНИЯ\n\n * закрытоугольная глаукома;\n * атрофический ринит;\n * операции на черепе, осуществленные через полость носа (в анамнезе);\n * детский возраст до 6 лет;\n * повышенная чувствительность к трамазолина гидрохлориду или бензалкония гидрохлориду, а также к другим компонентам препарата.\n\n\n\n_С осторожностью:_\n\nПациентам с артериальной гипертензией, заболеваниями сердца, гипертиреозом, сахарным диабетом, гиперплазией предстательной железы, феохромоцитомой, порфирией препарат следует применять только по рекомендации врача в связи с наличием потенциального риска системной абсорбции препарата.\n\nСледует соблюдать осторожность при приеме ингибиторов МАО, трициклических антидепрессантов, вазопрессорных препаратов и антигипертензивных препаратов.","overSized","imageComparisonOptions",[],"reviewsCounters",{},"redemptionStats",[],"saleEndsDateIso","cashback","showMultipleFractionsCounter","promoTitle","promoDescription","promoLegalDescription","lowestRecentPrice","productDisclaimers",[1107],{"_1108":1109,"_274":1110},"details","Цена действительна только при заказе онлайн. 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